Best place to eat near Florence, SC, only stopping overnight.
RedBone Alley has great shrimp & grits, and their bronzed chicken is really divine. I've also had their chicken salad and fruit plate which is really fresh, and the portion size is large.
Another good place is the StarFire Grill - it's a mix of traditional and greek. The Polynesian chicken salad is tasty, as is the hurricane shrimp and crab.