Maison in Lancaster is great. 15-20 min away.
Rice and Noodles Vietnamese relocated from New Orleans after hurricane Katrina so there's a connection there and it may be the best "ethnic" option around. 10-15 min away.
If you like beer, the Bullshead in Lititz is a must. A great beer list and good food to boot. You could visit Appalachian Brewing company and do a beer tour. But Bullshead should be the anchor.
Tomato Pie Cafe in Lititz serves a great tomato pie and is convenient for a stroll thru Lititz Springs park or a visit to Wilbur Chocolate Factory.
Pour in Lancaster for a nice beer and wine list and good charcuterie.
Carmen and David's Creamery in Lancaster for truly great and unique flavors of ice cream.
Martin's Preztel bakery in Akron for a snack. Buy a bag and ask for a soft pretzel if they're baking.
The Green Dragon market in Ephrata (Fridays) and Central Market in Lancaster are unique but very different local experiences.
Some of these require a short drive, but If you live to eat, it will be worth it.
Go to www.lititzpa.com and click on Dining under the Shop/Dine tab for a listing in Lititz. A very short drive will yield Mojo asian fusion at www.mojolancaster.com, this restaurant has a Lititz address and is not in Lancaster. Ciro's at www.ciroslancaster.com, is next to Lititz but again not in Lancaster city. Good luck and hope you have a great stay in Lititz!