Is this for Friday, Saturday, or Sunday? Are you willing to eat early or late? It's quite last minute to be looking for a reservation for 2 people at 8pm on Saturday night especially in those neighborhoods.
What is the amount you wish to spend before tax, tip, and drinks? It's best to give a figure that is for food only.
Without knowing your parameters, I did a quick search of OpenTable and found tables at:
Dell'anima - off peak times only
Il Buco Alimentari - Noho, one 7pm table, I'd grab it quick if you want to eat there
Peasant - 6:30 or 9:30
Rubirosa - 5:45