Otto or Frankies 570
Frankies, of the two, hands down. Either location (the new 570 or Frankies 17 on Clinton St.)
Another good option, Caffe Falai in Soho - they're more pure Italian & less Italian-American, though, so depends what you're looking for. When I'm in need of a pasta fix, it's them or Frankies for me, usually. Falai has a lighter hand and brighter flavors, you'll be satisfied but not in a food-coma afterwards. Frankies is more indulgent, rich. Both awesome, though.
Otto, for whatever reason, never been a huge fan of - and I quite like most of Batali's places.
1 Fifth Avenue, New York, NY 10003
265 Lafayette St, New York, NY 10012
We went to Frankies 17 on friday night, quite late, and it was busy right til midnight. I got the ricotta crostini and sweet potato ravioli - both were absolutely delicious. I was still hungry, though, and it didn't quite fill me up, so I ordered a side of broccoli rabe. That was the only disappointing part of the meal; it's served cold, which was kind of unexpected, and it was just...blah. My friend got the cavatelli and thought it was excellent. Definitely would go back.
Frankies 17 Spuntino
17 Clinton St, New York, NY 10002