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The above suggestions are all good, but if you are looking for red-sauce Italian-American I would add Rubirosa. It is on Mulberry St., just a couple of blocks north of Little Italy, and the food is far superior to the Little Italy places. For something more sophisticated, try Ciano (listed above in kathryn's post) on east 22nd st., another relative newcomer that is turning out some very serious food. We were there last night for the second time, and it's really exceptional.
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Other upscale Italian options:
Alto
Lincoln
FelidiaI haven't been to Il Mulino, Il Matto, Casa Lever, Porsena, and Novita, but these are worth exploring as well.
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Il Mulino
86 W 3rd St, New York, NY 10012Felidia
243 E 58th St, New York, NY 10022Novita
102 E 22nd St, New York, NY 10010Casa Lever
390 Park Avenue, New York, NY 10022Il Matto
281 Church St, New York, NY 10013Porsena
21 E 7th St, New York, NY 10003 -
I'd stay out of Little Italy personally. There are other places to go if you want red sauce Italian-American.
Italian is very hot in NYC right now. I would start researching:
Marea - especially for seafood
Convivio
Babbo
Del Posto - especially their weekday prix fixe lunch deal
Scarpetta
Locanda Verde
Esca - especially for seafood and their crudo
Osteria Morini
Ai Fiori
Maialino
CianoAnd for less expensive (but not exactly cheap)
Po
Peasant
Lupa
L'Artusi
Crispo
Falai
'ino and 'inotecaThere's probably more I'm forgetting!
Babbo vs Scarpetta
http://chowhound.chow.com/topics/758509Best Italian for my NY Foodie trip
http://chowhound.chow.com/topics/690834Where does a NY visitor find THE BEST Italian food?
http://chowhound.chow.com/topics/729968Ex-NY Hound visiting from LA - help me get my italian fix!
http://chowhound.chow.com/topics/755827Upscale Italian for lunch/dinner: Marea/Scarpetta/Convivio?
http://chowhound.chow.com/topics/755372Affordable Rustic Italian near Greenwich Village
http://chowhound.chow.com/topics/727522Italian: I've narrowed it down to Five...
http://chowhound.chow.com/topics/716226Best pasta
http://chowhound.chow.com/topics/725661-----
Lupa
170 Thompson Street, New York, NY 10012Babbo
110 Waverly Pl, New York, NY 10011Del Posto
85 10th Avenue, New York, NY 10011Crispo
240 W 14th St, New York, NY 10011Falai
68 Clinton St, New York, NY 10002Scarpetta
355 West 14th Street, New York, NY 10014Convivio
45 Tudor City Place, New York, NY 10017L'Artusi
228 West 10th Street, New York, NY 10014Marea
240 Central Park South, New York, NY 10019Locanda Verde
377 Greenwich St, New York, NY 10013›1 Reply -