Recs for Denver?
There have numerous posts with recommendations for downtown Denver -- often the same places recommended, re-recommended and re-re-recommended. Downtown Denver is not all that large, so everything in the downtown grid, the Platte Valley on the other (west-ish) side of the railroad tracks is w/in reasonable range. One thing to note is that places right near Coors Field tend to get jammed before a game. Plenty of pubs and sports bars to absorb much of the post-game crowd.
Highlands (NW Denver) and Uptown (east of downtown) have many dining options too. So does Cherry Creek North, which also offers Denver's best shopping -- if that's part of the game plan.
I'm with Claire—search for "downtown Denver" first, because it'll allow you to glean a load of info and then ask more targeted questions if need be that people might actually answer. It also, of course, depends on what you mean by "local flavor"—for instance, a lot of the best Mex hole in the walls aren't downtown.