Lisa: If you stick to West Des Moines, you may miss some of Des Moines best. Take a look at these post from the past two years.
Depending where you are to the west, I would have at least three suggestions, all of them local. First, Sage in Windsor Heights makes everyone's top ten list.
Second, in Clive is Cosi Cucina, which clearly bests the Biaggi chain.
Finally, You might try Sam and Gabe's.
Hope your trip is a good one and report back on your experience. PS, bring a warm coat!
Vern's doesn't look like much from the outside -- it is located next door to a muffler shop in a strip mall -- but I have had a number of wonderful meals here. It is definitely one of the best restaurants in the Waukee-Clive-West Des Moines area. The waitstaff is attentive, the food plentiful, and the atmosphere pleasant. Highly recommended.
Vern's Restaurant & Lounge
15970 Hickman Rd, Clive, IA