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I second Olives.. very work appropriate.. Blue Owl is a little southeast of U. Square but they have GREAT cocktails, especially martinis, and it's a little more intimate of a scene. I may get some backlash from this but Sidebar (although technically a sports bar) around 15th and 3rd has a separate restaurant section with drinks and great food - it's fun and nice but not overly upscale - depends what you are looking for.
The front section of Haru or Japonais are both also nice for drinks (their lychee martinis are delicious) after work.
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