Upscale Asian Fusion?
Not sure how UPSCALE the restaurant needs to be. However, I will recommend "All Seasons Table" which is located at 64 pleasant stree in Malden. If you search the board you will find numerous postings about this restaurant. I think they have very good sushi for the price - I especially like the "Chirashi Dunbori"
Good Indian restaurants with a Desi Chinese section on their menus: Namaskar, Grain and Salt, Punjab Palace.
French/Indian fusion: Mantra (though frankly I haven't been for dinner in a looong time.)
French and mostly South Asian fusion, with some other influences (Viet, Thai, Japanese): Banq.
French/Japanese (though much subtler fusion than most): Clio
Upscale in what sense? Price? Decor? It's more mid-scale pricewise but Gari in Coolidge Corner is the only fusion place in the area that I actually like. It's predominantly Japanese, with some American influence, and pulls it off well. It's quite small, a dozen or so two-tops plus a few seats at the sushi bar, with a modern, tasteful decor and very friendly service.
187 Harvard St, Brookline, MA 02446