Susta Strudl, Prague
If you walk from the Old Town Square, it would take you about 20 minutes. I am sure that trams are fine as the tram system in Prague is brilliant, but I wouldn't know which tram to take as I love walking in Prague, unless my destination is simply too far. The place is very easily found, you basically walk a large street, "Husitska", all the way up. It becomes "Konevova" at some point, and you have to turn right, into Chodovska I think. Consult a map, it should not be a problem. However, the area, Zizkov, is not the best part of town. At least it is not touristy.