Gluten Free Dining
I'm not sure why you need a restaurant that is totally gluten-free. My daughter's b.f. has that problem, and he manages to eat very well in all kinds of restaurants. He's just careful to avoid dishes that don't meet his dietary needs. That said...
A quick Google search finds risoterria, an Italian restaurant that participates in the "Gluten-Free Restaurant Awareness Program."
And here's a blog by someone who discusses options for gluten-free dining. (Note: She includes risotteria.)
For options in the other boroughs, post on the Outer Boroughs board.
Bratsncheesecurds, I don't know of any restaurant other than Risotteria that markets itself as being a gluten free restaurant, but some good cuisines to try that are safe for people with celiac disease (or a wheat intolerance) include south Indian (most dosas are made with lentil and rice flour; you'll want ot avoid sada dosai) and Thai or Vienamese (you'll want to make it clear that you cannot have even a drop of soy sauce in your food, though). There are usually safe dishes at any restaurant, though--even Italian (you can ask for plain, grilled fish with lemon and rice).
Name cuisines you like and I'll be able to name more restaurants / suggest menu items.
It's important that a restaurant be totally gluten-free or have a gluten-free menu because of cross contamination. One of my best friends has celiac, is extremely sensitive to gluten, and loves to eat out. Together, we've made an effort to find quality restaurants in the city that meet her needs. I agree with all the posters who suggested Risotteria and Babycakes. Both are godsends for people with gluten sensitivity. I especially recommend the brownies at Babycakes. Other great restaurants with gluten-free menus include Gobo, Sacred Chow (vegan chow in the West Village), Gus' Place (gluten-free Greek in the West Village) and Gourmetland (gluten-free Chinese at 82nd and 2nd). My friend has also been able to eat at Caracas Arepa Bar in the East Village and Village Yokocho with no problem.
Gus's Place isn't gluten free per se; it just has a special notation on the menu for its gluten free menu items.
There is a danger of cross contamination in almost all restaurants--even the ones that have special, gluten free menus--but most good kitchens will take extra precautions esp.if you call ahead. WD 50, for one, can design a gluten free tasting menu for you.
Caracas A.B.is a good suggestions. Along the same lines, Flor's Kitchen in the W. Village would work, too.
not a sit down restaurant, but a standard new york pizza slice counter place... mozzarelli's (23rd btwn Madison & Park) stands out for offering gluten free and spelt-bread pizza by the slice as well as sandwiches with the same bread. tasty... though if you're on a very strict version of the diet... they do not guarantee no minor cross-contamination with other flours.
I came across this website, which lists all of the restaurants in NYC that offer gluten-free meals or bakery items - http://thiscakeisjustasgood.com
Some have already been mentioned here by other users. Maps and links to each place are available on the site as well.
Sugar Free, Wheat Free, Gluten Free, Vegan
Charming Italian Restaurant located at 415 3rd Avenue (At 29th St & 3rd Ave) New York, New York 10016
Bloom's Delicatessen Cafe
Dinner style menu with large portions
Mexican fare made from fresh ingredients and, like the rest of the food, the guacamole (Gluten Free) is not from a mix so its pretty easy to find something safe to eat. The waitstaff knows the ingredients is helpful with related questions.
Vegetarian dining at two Manhattan locations
Carrabba's Italian Grill
This Italian restaurant is located throughout the United States and offers a gluten free menu along with their standard offerings in a casual, warm, festive atmosphere.
Gluten Free Restaurants NYC Map
This Map will let you quickly make a choice of a gluten free restaurant based on location. See all gluten free restaurants in Manhattan in one place. Did I miss one? Let me know!
Daily dining, deliver and take-out: healthy vegetarian dining for everyone.
Mediterranean Lunch and Dinner in Grenwich Village with outdoor and indoor dining.
Delicious and healthy fresh fruit smoothies made to order, gluten free menu items clearly listed
An Australian steakhouse concept open for dinner only. Although beef and steak items make up a good portion of the menu, the concept offers a variety of chicken, ribs, seafood, and pasta dishes.
American diner or pub fare & cocktail bar
Risotteria Italian Restaurant and Bakery
Casual West Village, specialty Italian restaurant and gluten free bakery with table-service, take-out and delivery. A selection of gluten-free beer
Family Style Italian Dining, Manhattan
Tini Ristorante Italiano
Italian Dinner menu with full bar and raw bar. Takeout, delivery and catering too!
Tropica Bar & Seafood House
Latin Asian Power Lunch
a supermarket for all your specialty needs. They provide a shopping list of gluten-free items and typically carry products that clearly label ingredients of concern. Stores include a sit-down restaurant with fresh fruit smoothie bar.
"down-home" American style cuisine on Long Island
Just wanted to report that I tried out Mozzarelli's GF pizza today. THey are square slices, and they had three varieties: veggie, sausage, pepperoni, and cheese. It wasn't as crispy as I would have liked, the sauce left a bit to be desired, and there could have been more cheese, but given that it EXISTED, that in itself was an accomplishment. The crust did have a nice chew, perhaps due to the fact that it was made with pinto and garbanzo bean flour (which also means that it was a bit healthier than your standard rice flour crust.) All in all, not bad. Different from risotteria, which is crispier, and better in that respect, but definitely serviceable. I'll definitely go again.