If you have access to a car, your choices are limitless. How old are the parties you will be traveling with? South City Kitchen is wonderful and within walking distance, but be aware that the space is pretty tight and can be quite noisy. It may not be appropriate for very young children. Food-wise, Einstein's is okay, but the porch and patio is good for kids and it's a quick walk from the High Museum. Further down at Piedmont and 14th, there are several restaurants that are family friendly.
If you have transportation, Mary Mac's on Ponce de Leon is a southern restaurant, and a great place for families. Alon's on Highland Ave. is a fantastic bakery that makes wonderful sandwiches. Java Jive on Ponce de Leon is a funky breakfast joint.
Thanks for all of these suggestions. They are very helpful. The parties involved include 3 generations ranging in age from 8 months to grandparents at 66. All are fairly well-behaved and reasonably adventurous diners (ok, the grand parents aren't really always too adventurous). We will have a car but would prefer to keep the driving to a minimum. We had been thinking about Mary Mac's and South City Kitchen so good to see recommendations for those. Any ones in particular you recommend around Piedmont and 14th St. Thanks again.
there are a ton of great restaurants in that area, as far as family friendly near the High i would recommend:
South City Kitchen (on crescent) - good southern food
Murphys (at virginia and highland) - good all around food with a great wine list
La Tavola Trattoria (also at virginia and highland) - italian
vortex (on peachtree) great hamburgers