I ate at Urena several months ago. I can't remember most of what I ate, but do remember it was a good (even very good), inventive meal. The space is a bit strange, sort of sterile, but the food and service overcome it.
In the same area, Parea has gotten some good buzz for its creative take on Greek cuisine. Frank Bruni reviewed it in the Times recently:
I have not been to Urena yet, but from what I've read, chef/owner Alex Urena is serving some very interesting cuisine. He at one time spent some time with Adria, though there has been a debate as to how much influence that is having on his cooking now. There's a menu with prices on menupages.com. No way to know how up-to-date it is.